| | db_trialID | db_groupID | db_PrimarySiteCode1 | db_PrimarySiteCode2 | Endorsed By | Protocol Description | Eligibility |
| 5 |
1
| RTOG 0625/ACRIN 6677 | Recurrent GBM TEMPORARILY CLOSED |
BRAIN
RTOG 0625/ACRIN 6677
Recurrent GBM TEMPORARILY CLOSED
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 2 | 5 | 2 |
Medical Oncology
|
| 148 | 5 | 6 |
AK CHO
|
| A Randomized Phase II Trial of Bevacizumab with Irinotecan or Bevacizumab with Temozolomide in recurrent GBM |
| db_EligibilityTrialID | db_trialID | |
| 7 | 5 |
- Pt must have rec’d prior temozolomide
|
| 8 | 5 |
- Prior tx with SRS, Gliadel wafer or brachytherapy okay
|
| 10 | 5 |
- Unequivocal radiographic evidence for progression by MRI within 14 days
|
| 289 | 5 |
- Contact (561) 955-4800
|
| 463 | 5 |
-
|
|
| 6 |
1
| RTOG 0627 | Recurrent GBM TEMPORARILY CLOSED |
BRAIN
RTOG 0627
Recurrent GBM TEMPORARILY CLOSED
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 4 | 6 | 1 |
Radiation Oncology
|
| 5 | 6 | 2 |
Medical Oncology
|
| Phase II Trial of Dasatinib in patients with recurrent GBM treated with RT + temozolomide |
| db_EligibilityTrialID | db_trialID | |
| 11 | 6 |
- MRI or CT brain done within 10 days prior to registration
|
| 12 | 6 |
- Gliadel wafer use excluded
|
| 13 | 6 |
- Scan showing recurrent/progressive GBM
|
| 290 | 6 |
- Contact (561) 955-4800
|
| 462 | 6 |
-
|
|
| 8 |
1
| NCCTG 0574 | Cerebral Mets |
BRAIN
NCCTG 0574
Cerebral Mets
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 8 | 8 | 1 |
Radiation Oncology
|
| Phase III Randomized Trial of the Role of Whole Brain RT in Addition to Radiosurgery in Patients with 1 to 3 Cerebral Metastases |
| db_EligibilityTrialID | db_trialID | |
| 16 | 8 |
- 1-3 presumed brain mets from a histologically confirmed extra-cerebral tumor site (lung, breast, prostate)
|
| 17 | 8 |
- Will receive tx with a gamma knife or a linear accelerator-based SRS system
|
| 291 | 8 |
- Contact (561) 955-4800
|
|
| 11 |
2
| NSABP B39 | WBI vs PBI |
BREAST
NSABP B39
WBI vs PBI
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 13 | 11 | 1 |
Radiation Oncology
|
| A Randomized Phase III Study of Conventional Whole Breast Irradiation vs. Partial Breast Irradiation for Women with Stage 0, I or II Breast Cancer |
| db_EligibilityTrialID | db_trialID | |
| 24 | 11 |
- DCIS or invasive ca, stage 0, I or II
|
| 25 | 11 |
- Tumor less than or equal to 3 cm
|
| 26 | 11 |
- DCIS – must be < 50 y/o, any ER/PR
|
| 27 | 11 |
- Invasive ca EXCLUDED if > or = 50 y/o AND node neg AND receptor positive
|
| 294 | 11 |
- Contact (561) 955-4800
|
|
| 12 |
2
| ECOG PACCT-1 | Oncotype score to determine tx assignment |
BREAST
ECOG PACCT-1
Oncotype score to determine tx assignment
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 14 | 12 | 2 |
Medical Oncology
|
| Trial Assigning Individualized Options for Treatment using Oncotype DX Assay Recurrence Score (RS 11-25 are randomized to chemo + hormonal tx OR hormonal tx only ; <11 receive only hormonal tx and > 25 receive chemo and hormonal tx)
Register before or after
|
| db_EligibilityTrialID | db_trialID | |
| 28 | 12 |
- ER + and/or PR +
|
| 29 | 12 |
- Her2/neu not over-expressed
|
| 30 | 12 |
- Axillary node negative & age < 75
|
| 31 | 12 |
- Tumor 1.1 to 5 cm or 5 mm to 1 cm and unfavorable histological features
|
| 32 | 12 |
- Candidate for chemo + hormonal therapy
|
| 262 | 12 |
- Placement of MammoSite excludes pt
|
| 295 | 12 |
- Contact (561) 955-4800
|
|
| 19 |
2
| NCIC MA17R | Hormonal Therapy |
BREAST
NCIC MA17R
Hormonal Therapy
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 19 | 19 | 2 |
Medical Oncology
|
| Phase III Randomized Double-Blind Randomization to Letrozole or Placebo for women previously diagnosed with breast cancer completing five years of AI either as initial therapy or after tamoxifen |
| db_EligibilityTrialID | db_trialID | |
| 56 | 19 |
- Invasive breast cancer (DCIS excluded)
|
| 57 | 19 |
- Must have completed 4.5-6 years of an AI
|
| 58 | 19 |
- May have rec’d tamoxifen prior to AI
|
| 59 | 19 |
- Last dose of AI and randomization must be < 2 years
|
| 297 | 19 |
- Contact (561) 955-4800
|
|
| 20 |
2
| NSABP B42 | Hormonal Therapy |
BREAST
NSABP B42
Hormonal Therapy
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 21 | 20 | 2 |
Medical Oncology
|
| A Clinical Trial to Determine the Efficacy of Five Years of Letrozole Compared to Placebo in Patients Completing Five Years of Hormonal Therapy Consisting of and AI or Tamoxifen Followed by an AI in Prolonging Disease-Free Survival in Post-Menopausal Women with Hormone Receptor Positive Invasive Br |
| db_EligibilityTrialID | db_trialID | |
| 60 | 20 |
- Duration of initial hormonal therapy may be 57-63 months, pt must be randomized within 6 months following completion;
|
| 61 | 20 |
- Therapy must have been an AI or up to 3 years of tamoxifen followed by an AI, no tamoxifen during years 4 and 5
|
| 62 | 20 |
- Can pre-register pt to receive letrozole at no cost to complete the 5 years of tx if:
|
| 63 | 20 |
- A) 2-4.5 years of AI; or B) 2-3 years tamoxifen; or C) 2-4.5 years combination of tamoxifen (≤ 3 years) followed by an AI
|
| 303 | 20 |
- Contact (561) 955-4800
|
|
| 24 |
2
| SWOG 0226 | Metastatic-hormonal therapy |
BREAST
SWOG 0226
Metastatic-hormonal therapy
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 23 | 24 | 2 |
Medical Oncology
|
| Phase III Randomized Trial of Anastrozole Versus Anastrozole and Fulvestrant as First Line Therapy for Post Menopausal Women With Metastatic Breast Cancer
|
| db_EligibilityTrialID | db_trialID | |
| 81 | 24 |
- Dx of metastatic ca or multiple sites of new disease (multiple sites of new osseous disease)
|
| 82 | 24 |
- ER and/or PR positive
|
| 83 | 24 |
- No prior chemo/hormones or immunotherapy for recurrence or mets
|
| 304 | 24 |
- Contact (561) 955-4800
|
|
| 80 |
2
| ECOG 5103 | Chemotherapy, 1st line |
BREAST
ECOG 5103
Chemotherapy, 1st line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 106 | 80 | 2 |
Medical Oncology
|
| A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide followed by Paclitaxel with Bevacizumab or Placebo in Pts with lymph
Node Positive and High Risk Lymph Node Negative Breast Cancer
|
| db_EligibilityTrialID | db_trialID | |
| 252 | 80 |
- Patients must meet at least one of the following: A) at least one positive axillary lymph node; B) ER neg tumor ≥1cm; C) ER + ≥ 5 cm; C) ER + ≥1cm but < 5 with a RS of ≥ 11 (ok if enrolled in TAILOR
|
| 300 | 80 |
- Contact (561) 955-4800
|
|
| 111 |
2
| Senorx | Contura™ (MLB) |
BREAST
Senorx
Contura™ (MLB)
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 140 | 111 | 1 |
Radiation Oncology
|
| A Multi-Site Prospective, Non Randomized Study Utilizing the Contura™ Multi-Lumen Balloon (MLB) Breast Brachytherapy Applicator to Deliver Accelerated Partial Breast Irradiation: Analysis of Dosimetric Success, Local Tumor Control, Cosmetic Outcome, Acute and Chronic Toxicity, and Clinical Scenarios for Optimal Use |
| db_EligibilityTrialID | db_trialID | |
| 424 | 111 |
- Age 50 or older with life expectancy greater than 10 years
|
| 425 | 111 |
- DCIS and/or invasive, size ≤ 3 cm
|
| 426 | 111 |
- ER positive, unilateral disease
|
| 427 | 111 |
- If invasive ca, either SNB alone if neg; or minimum 6 axillary nodes removed and all negative
|
| 428 | 111 |
- Excluded if prior breast cancer
|
| 429 | 111 |
- Contact (561) 955-4800
|
|
| 86 |
2
| NCCTG 063D ALTTO | Chemotherapy-1st line |
BREAST
NCCTG 063D ALTTO
Chemotherapy-1st line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 108 | 86 | 2 |
Medical Oncology
|
| A Randomised, Multi-Centre, Open-Label, Phase III Study of Adjuvant Lapatinib,
Trastuzumab, their Sequence and their Combination in Patients with HER2/ErbB2 Positive Primary Breast Cancer
|
| db_EligibilityTrialID | db_trialID | |
| 271 | 86 |
- Pt will receive targeted therapy after all chemo or concurrently with paclitaxel
|
| 272 | 86 |
- HER2 gene amplification required
|
| 273 | 86 |
- Node + or node negative with tumor > or = 1 cm
|
| 302 | 86 |
- Contact (561) 955-4800
|
|
| 129 |
2
| U-Systems somoInSIGHT | |
BREAST
U-Systems somoInSIGHT
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 157 | 129 | 3 |
Radiology/Women’s Center
|
| A Clinical Study to Evaluate Somo•v and Digital Mammography Together as a Breast Cancer Screening Method, Compared to Digital Mammography Alone, in Women With Dense Breasts. (somo•InSIGHT) |
| db_EligibilityTrialID | db_trialID | |
| 514 | 129 |
- Female age 25 or older
|
| 515 | 129 |
- Asymptomatic
|
| 516 | 129 |
- Prior screening mammograms, if available, exhibit history of breast density
|
| 517 | 129 |
- Not currently pregnant or breastfeeding, or planning for these within next 18mos
|
| 518 | 129 |
- No breast surgeries or interventional procedures in the past 12 months
|
| 519 | 129 |
- No history of cancer diagnosis and/or treatment in the past 12 months
|
| 520 | 129 |
- > 50% preliminary parenchymal density on preliminary assessment by technologistFemales aged 25 or older
|
|
| 130 |
2
| High Risk PEM/MRI | |
BREAST
High Risk PEM/MRI
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 158 | 130 | 3 |
Radiology/Women’s Center
|
| Positron Emission Mammography (PEM) Compared to Magnetic Resonance Imaging (MRI) of the Breast as Screening Tool for Women with High Risk for Developing Breast Cancer |
| db_EligibilityTrialID | db_trialID | |
| 521 | 130 |
- Female age 25 or older
|
| 522 | 130 |
- Assessed to have >25% lifetime risk of breast cancer on basis of one of the following: BRCA positive, family history consistent with Hereditary Breast and Ovarian Cancer with a negative BRCA test result in either an affected family member or if none available, negative test result in subject, LCIS history, GAIL score >25% lifetime risk, or history of Hodgkin's disease treated with mantle radiatio
|
| 523 | 130 |
- Up-to-date mammography w/o suspicious findings or with negative work up of suspicious finding
|
| 524 | 130 |
- Current clinical breast exam
|
|
| 76 |
3
| NCCTG 0147 | Colon-1st line |
GI
NCCTG 0147
Colon-1st line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 112 | 76 | 2 |
Medical Oncology
|
| Randomized Phase III Trial of FOLFOX +/- cetuximab after curative resection for patients with Stage III Colon Cancer |
| db_EligibilityTrialID | db_trialID | |
| 245 | 76 |
- Stage III disease, resected
|
| 246 | 76 |
- Radomization < 56 days post surgery
|
| 311 | 76 |
- Contact (561) 955-4800
|
|
| 112 |
3
| NSABP 0822 | Rectal, 1st line |
GI
NSABP 0822
Rectal, 1st line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 141 | 112 | 1 |
Radiation Oncology
|
| 142 | 112 | 2 |
Medical Oncology
|
| A Phase II Evaluation of Pre-op Chemo-RT Utilizing IMRT in Combination with Capecitabine and Oxaliplatin for Patients with Locally Advanced Rectal Cancer
|
| db_EligibilityTrialID | db_trialID | |
| 430 | 112 |
- Dx of rectal ca and colonoscopy within 56 days
|
| 431 | 112 |
- Transrectal US for T stage, unless other exam demonstrates T4
|
| 432 | 112 |
- Contact (561) 955-4800
|
|
| 65 |
3
| CALGB 80405 | Metastatic colorectal |
GI
CALGB 80405
Metastatic colorectal
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 113 | 65 | 2 |
Medical Oncology
|
| A Phase III Trial of FOLFOX or FOLFIRI
with bevacizumab or cetuximab or both
for Pts with Untreated Metastatic Adenocarcinoma of the Colon or Rectum
|
| db_EligibilityTrialID | db_trialID | |
| 204 | 65 |
- Locally advanced or metastatic colorectal cancer
|
| 205 | 65 |
- No prior treatment for advanced or metastatic colorectal cancer
|
| 206 | 65 |
- FOLFOX or FOLFIRI may be chosen by physician
|
| 310 | 65 |
- Contact (561) 955-4800
|
|
| 25 |
3
| Esophagus/Gastric | CALGB 80101 |
GI
Esophagus/Gastric
CALGB 80101
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 110 | 25 | 2 |
Medical Oncology
|
| 111 | 25 | 1 |
Radiation Oncology
|
| A Phase III Trial of Adjuvant Chemoradiation after Resection of Gastric and Gastroesophageal Adenocarcinoma |
| db_EligibilityTrialID | db_trialID | |
| 84 | 25 |
- IB, II, IIIA, IIIB or IV with M0
|
| 85 | 25 |
- No prior chemo or RT
|
| 306 | 25 |
- Contact (561) 955-4800
|
|
| 29 |
3
| ECOG 5202 | Colon-Molecular Markers |
GI
ECOG 5202
Colon-Molecular Markers
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 25 | 29 | 2 |
Medical Oncology
|
| Randomized Phase III Study Comparing 5-FU, Leucovorin and Oxaliplatin +/- Bevacizumab in Patients with Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers High-risk patients randomized to tx arms, low-risk pts randomized to observation |
| db_EligibilityTrialID | db_trialID | |
| 86 | 29 |
- Tumor must be ≥ 12 cm from anal verge by endoscopy or surgical exam
|
| 87 | 29 |
- Tumor specimen must be avialale for eval of microsatellite instability and loss of heterozygosity at 18q, to determine high risk versus low risk tx assignment
|
| 88 | 29 |
- Stage II = T3 or T4, N0, M0
|
| 89 | 29 |
- Must have ≥ 8 lymph nodes evaluated
|
| 90 | 29 |
- Must have ≥ 8 lymph nodes evaluated
|
| 307 | 29 |
- Contact (561) 955-4800
|
|
| 31 |
3
| Amgen, Spiritt | Colorectal, Metastatic, 2nd Line |
GI
Amgen, Spiritt
Colorectal, Metastatic, 2nd Line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 80 | 31 | 5 |
SG CHO
|
| Randomized, Phase 2 study of FOLFIRI with Panitumumab or Bevacizumab as Second-line Treatment in Subjects with Metastatic Colorectal Cancer after FOLFOX |
| db_EligibilityTrialID | db_trialID | |
| 91 | 31 |
- ECOG 0-1
|
| 92 | 31 |
- Measurable disease
|
| 93 | 31 |
- No use of CYP3A4 inducers, inhibitors, and substrates
|
| 330 | 31 |
- Contact (561) 955-6613
|
|
| 34 |
3
| NSABP R04 | Rectal |
GI
NSABP R04
Rectal
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 36 | 34 | 1 |
Radiation Oncology
|
| 37 | 34 | 2 |
Medical Oncology
|
| Comparing Preop RT and Capecitabine +/- oxaliplatin with Preop RT and Continuos IV Infusion of 5-FU +/- oxaliplatin in the Tx of Patients with Operable |
| db_EligibilityTrialID | db_trialID | |
| 207 | 34 |
- MUST have transluminal ultrasound for staging
|
| 208 | 34 |
- Diagnosis of invasive rectal cancer by surgical or endoscopic biopsy
|
| 209 | 34 |
- Time between diagnosis and treatment < 42 days
|
| 309 | 34 |
- Contact (561) 955-4800
|
|
| 36 |
4
| Renal cell | ECOG 2805 |
GU
Renal cell
ECOG 2805
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 53 | 36 | 2 |
Medical Oncology
|
| A Randomized, Double-Blind Phase III Trial of Adjuvant Sunitinib versus Sorafenib versus Placebo in Pts with Resected Renal Cell Ca |
| db_EligibilityTrialID | db_trialID | |
| 100 | 36 |
- Primary-intact renal cell ca, eligible for nephrectomy with curative intent
|
| 101 | 36 |
- Randomize 3-10 weeks after surgery
|
| 312 | 36 |
- Contact (561) 955-4800
|
|
| 75 |
4
| ECOG 5805 | Prostate |
GU
ECOG 5805
Prostate
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 117 | 75 | 2 |
Medical Oncology
|
| Phase II Trial of E7389 (Halichondrin B Analog) in Patients with Metastatic Hormone Refractory Prostate Cancer |
| db_EligibilityTrialID | db_trialID | |
| 242 | 75 |
- 1st line, 2nd line or 3rd line
|
| 243 | 75 |
- Progressive mets (new/enlarging lesions) or stable mets and rising PSA (4 weeks)
|
| 244 | 75 |
- Must have had prior tx with bilateral orchiectomy or other primary hormonal therapy with evidence of tx failure
|
| 314 | 75 |
- Contact (561) 955-4800
|
|
| 131 |
4
| Novartis CRAD001L2202 | Met renal cell 1st line/2nd line |
GU
Novartis CRAD001L2202
Met renal cell 1st line/2nd line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 159 | 131 | 6 |
AK CHO
|
| Open-label, multicenter phase II study to compare the efficacy and safety of RAD001as first-line followed by second-line sunitinib versus sunitinib as first-line followed by second-line RAD001 in the treatment of patients with metastatic renal cell carcinoma. |
| db_EligibilityTrialID | db_trialID | |
| 525 | 131 |
- Clear cell(or component) or non-clear cell
|
| 526 | 131 |
- W/or W/O nephrectomy (partial or total)
|
| 527 | 131 |
- KPS≥70
|
| 528 | 131 |
- At least 1 measureable lesion
|
| 529 | 131 |
- No prior systemic tx for metastatic RCC
|
| 530 | 131 |
- Contact 561-955-6613
|
|
| 42 |
5
| Dana Farber Cancer Inst PARADIGM | Locally advanced |
HEAD and NECK
Dana Farber Cancer Inst PARADIGM
Locally advanced
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 42 | 42 | 2 |
Medical Oncology
|
| 43 | 42 | 1 |
Radiation Oncology
|
| A Randomized Phase III Trial Comparing Sequential Therapy With TPF/Chemoradiation (ST) To Cisplatin-Based Chemoradiotherapy with Accelerated Concomitant Boost Radiotherapy (CRT) For Locally Advanced Squamous Cell ca of the Head and Neck
|
| db_EligibilityTrialID | db_trialID | |
| 124 | 42 |
- Squamous cell ca of head and neck
|
| 125 | 42 |
- Primary sites: oral cavity, oropharynx, hypopharynx or larynx
|
| 126 | 42 |
- Stage III or IV without distant mets
|
| 127 | 42 |
- No prior chemo or RT ever for any dx
|
| 128 | 42 |
- No prior surgery for SCCHN
|
| 316 | 42 |
- Contact (561) 955-4800
|
|
| 127 |
6
| Celgene002 Continuum | CLL Maintenance after 2nd line |
LEUKEMIA
Celgene002 Continuum
CLL Maintenance after 2nd line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 155 | 127 | 8 |
HA CHO
|
| Randomized, double-blind, placebo-controlled, parallel-group study of lenalidomide as maint. therapy in B-cell CLL following second line therapy |
| db_EligibilityTrialID | db_trialID | |
| 501 | 127 |
- 1st or 2nd regimen must contain purine analog
|
| 502 | 127 |
- Minimal response of partial response after 2nd line
|
| 503 | 127 |
- Last 2nd line theray>8 weeks and <16 weeks prior to randomization
|
| 505 | 127 |
- ECOG ≤2
|
| 506 | 127 |
- Contact 561-955-6613
|
|
| 123 |
6
| CLL Phase III | 2nd line GSK913 |
LEUKEMIA
CLL Phase III
2nd line GSK913
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 152 | 123 | 8 |
HA CHO
|
| Open label, randomized Ofatumumab+Fludarabine-Cyclophosphamide vs Fludarabine-Cyclophosphamide alone in relapsed CLL |
| db_EligibilityTrialID | db_trialID | |
| 485 | 123 |
- +CD5, CD19, CD20, CD23, CD79b and surface Ig
|
| 486 | 123 |
- Active disease
|
| 487 | 123 |
- At least 1 prior CLL therapy; must have had CR or PR
|
| 488 | 123 |
- ECOG 0-2
|
| 489 | 123 |
- No prior stem cell transplant
|
| 490 | 123 |
- Contact (561) 955-6613
|
|
| 87 |
7
| PrECOG 0501 | 1st line for IIIB, IV or recurrent NSCLC |
LUNG
PrECOG 0501
1st line for IIIB, IV or recurrent NSCLC
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 126 | 87 | 2 |
Medical Oncology
|
| A Randomized Phase II Study Evaluating Vandetanib in Combination with Docetaxel and Carboplatin +/- Placebo or Maintenance Therapy with Vandetanib in Patients with IIIB, IV or Recurrent NSCLC |
| db_EligibilityTrialID | db_trialID | |
| 266 | 87 |
- NSCLC stage IIIBor stage IV tht is primary or recurrent
|
| 267 | 87 |
- Prior adjuvant tx okay if > 1 year
|
| 268 | 87 |
- Prior malignancy okay if > 3 years
|
| 269 | 87 |
- Prior RT okay if > 2 weeks
|
| 270 | 87 |
- Brain mets okay if tx completed > 4 weeks and are stable without steroid therapy
|
| 326 | 87 |
- Contact (561) 955-4800
|
|
| 82 |
7
| ACRIN 6668/RTOG 0235 | Imaging |
LUNG
ACRIN 6668/RTOG 0235
Imaging
| Positron Emission Tomography Pre- and Post-treatment Assessment for Locally Advanced Non-small Cell Lung Carcinoma |
| db_EligibilityTrialID | db_trialID | |
| 254 | 82 |
- No prior RT, PS 0-1
|
| 255 | 82 |
- IIB or III NSCLC tx with chemo + RT (inoperable), OK if on another study
|
| 256 | 82 |
- Baseline whole body PET, then f/u whole body PET 12-16 weeks after XRT
|
| 325 | 82 |
- Contact (561) 955-4800
|
|
| 113 |
7
| ACRIN 6678 | |
LUNG
ACRIN 6678
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 143 | 113 | 2 |
Medical Oncology
|
| FDG-PET/CT as a Predictive Marker of Tumor Response and Patient Outcome: Prospective Validation in Non-small Cell Lung Cancer |
| db_EligibilityTrialID | db_trialID | |
| 433 | 113 |
- Newly dx IIIB or IV
|
| 434 | 113 |
- Recurrent or met NSCLC ok if tx was completed ≥ 3 mo. prior to enrollment with measurable lesion in the chest
|
| 435 | 113 |
- Plan to start tx w/ a platinum-based, dual-agent regimen at 3 week cycles
|
| 436 | 113 |
- Excluded if bevacizumab (Avastin) is planned at the initiation of chemo
|
| 437 | 113 |
- Contact (561) 955-4800
|
|
| 119 |
7
| SURGICAL | CALGB 140503 |
LUNG
SURGICAL
CALGB 140503
| Phase III Randomized Trial of Lobectomy vs. Sublobar Resection for Small (≤2cm) Peripheral NSCLC |
| db_EligibilityTrialID | db_trialID | |
| 459 | 119 |
- Peripheral lung nodule ≤ 2cm on CT and presumed to be lung cancer
|
| 460 | 119 |
- Location suitable for lobar or sublobar resection
|
| 461 | 119 |
- No prior chemo or RT for this disease
|
|
| 122 |
7
| Lilly H3E-JMHD | NSCL 1st line |
LUNG
Lilly H3E-JMHD
NSCL 1st line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 151 | 122 | 7 |
HG CHO
|
| Randomized, open-label, pemetrexed + carboplatin/bevacizumab followed by maint. pemetrexed/bevacizumab vs paclitaxel+ carboplatin/bevacizumab followed by maint. bevacizumab |
| db_EligibilityTrialID | db_trialID | |
| 479 | 122 |
- Stage IIIB w/ pleural effusion or IV disease
|
| 480 | 122 |
- No prior systemic chemo for NSCL/no adj. tx
|
| 481 | 122 |
- Measurable or nonmeasurable disease per RECIST
|
| 482 | 122 |
- No squamous cell histology
|
| 483 | 122 |
- Contact 561-955-6613
|
|
| 50 |
7
| ECOG 1504 | Advanced BAC |
LUNG
ECOG 1504
Advanced BAC
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 47 | 50 | 2 |
Medical Oncology
|
| Phase II Study of C225 (Cetuximab) for the Treatment of Patients with Advanced Bronchioloalveolar Carcinoma (BAC) or Adenocarcinoma with BAC Features |
| db_EligibilityTrialID | db_trialID | |
| 152 | 50 |
- Stage IIIB with pleural effusion or stage IV
|
| 153 | 50 |
- May have received up to 1 prior chemo regimen for advanced BAC
|
| 154 | 50 |
- See protocol for additional eligibility
|
| 321 | 50 |
- Contact (561) 955-4800
|
|
| 51 |
7
| PrECOG 1505 | Chemotherapy, 1st Line |
LUNG
PrECOG 1505
Chemotherapy, 1st Line
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 48 | 51 | 2 |
Medical Oncology
|
| Phase III Randomized Trial of Adjuvant Chemotherapy with or without Bevacizumab for Patients with Completely Resected Stage IB (> 4 cm) - IIIA NSCLC |
| db_EligibilityTrialID | db_trialID | |
| 155 | 51 |
- Complete resection of stage IB (> 4 cm) to IIIA (T2-3N0, T1-3N1, T1-3N2)
|
| 156 | 51 |
- Pt must be 6-12 weeks from thoracotomy
|
| 157 | 51 |
- Excluded if h/o CVA or TIA
|
| 323 | 51 |
- Contact (561) 955-4800
|
|
| 125 |
8
| NHL Celgene-001 | Mantle Cell Relapsed/Refractory Phase II |
LYMPHOMA
NHL Celgene-001
Mantle Cell Relapsed/Refractory Phase II
| db_researchSpecialtyID | db_trialID | db_SpecialtyID | |
| 153 | 125 | 8 |
HA CHO
|
| Single-arm, open-label, lenalidomide in patients with mantle cell NHL relapsed or progressed after tx with bortezomib or refractory to bortezomib |
| db_EligibilityTrialID | db_trialID | |
| 491 | 125 |
- ECOG0-2
|
| 492 | 125 |
- Must have had anthracycline/mitoxantrone, cyclophosphamide, rituximab, bortezomib
|
| 493 | 125 |
- Relapsed/refractory to bortezomib
|
| 494 | 125 |
- Relapsed after autologous stem cell transplant OK
|
| 495 | 125 |
- Calc. Cr Clearance ≥30 mL/min
|
| 496 | 125 |
- Contact (561) 955-6613
|
|
| 88 |
12
| Total Cancer Care™ | Multiple Disease Sites |
TCC™ TISSUE COLLECTION
Total Cancer Care™
Multiple Disease Sites
| Non-treatment study designed to create a centralized clinical data and tissue repository. Collection of excess tissue, both normal and tumor, removed from patient during surgical procedure or biopsy. |
| db_EligibilityTrialID | db_trialID | |
| 263 | 88 |
- Must be at least 18 years of age
|
| 264 | 88 |
- Patients with high clinical suspicion or who are diagnosed with localized, recurrent or metastatic cancer
|
| 265 | 88 |
- Patient will be followed for life
|
| 287 | 88 |
- Contact (561) 955-2273
|
|